P198 Exosome Healer / Exosome Skin Booster

P198 Exosome Skin Booster in Seoul

Medically reviewed by Dr. Chae-ho Lee, Medical Director, Doctorpetit Clinic Hongdae; Member, Korean Society of Clinical Aesthetic Medicine

Doctor profile · Doctorpetit Clinic Hongdae, Seoul

The P198 Exosome Healer is an exosome skin booster: an injectable or applied skin treatment containing exosomes taken from stem-cell culture fluid, used to support overall skin quality and texture. At Doctorpetit Clinic Hongdae in Seoul, Korea, a session takes roughly 15 to 30 minutes, and most people go back to their day straight afterward. Independent clinical evidence for cosmetic exosome products is still limited, so this page sets out what the clinic describes and where the research stands.

What Is the P198 Exosome Skin Booster?

The P198 Exosome Healer is a skin booster that the clinic describes as fifth-generation, built from microparticles that carry exosomes extracted from stem-cell culture fluid.

• Exosome content. Exosomes are tiny vesicles released by cells; this product uses exosomes taken from the fluid in which stem cells are cultured.
• Microparticle design. The clinic states that the small particle size is intended for deep penetration into the skin and high absorption.
• Collagen support. According to the clinic, the treatment promotes collagen synthesis, which is linked to firmness and texture.
• Problem-prone skin. The clinic describes anti-inflammatory and antibacterial effects that may help with skin concerns such as acne and atopic dermatitis.
• Gradual change. Any improvement develops over weeks rather than overnight, and a course of sessions is recommended.

Exosome boosters sit within the wider skin-booster category, which aims to improve the quality of the skin rather than change facial shape. Where a hyaluronic acid booster focuses on hydration, and a biostimulator focuses on encouraging collagen over time, exosome products are marketed around skin renewal and recovery. That positioning is a description of intent; it is not the same as proof from controlled trials.

Alternatives to consider

The exosome booster is one of several routes to better skin quality. Depending on your main concern, the clinic may also suggest a conventional skin booster, a laser treatment, or microneedling instead. If hydration is the priority, a hyaluronic acid booster may be the more direct choice. If uneven texture is the main concern, an energy-based or microneedling treatment may be discussed. The consultation is where Dr. Lee weighs these options against your skin, your schedule in Seoul, and how much evidence you want behind a treatment before choosing it.

What the evidence does and does not show

Research on exosomes in aesthetic dermatology is early. A 2025 literature review in the Journal of Cosmetic Dermatology noted that exosome products are not standardized in how they are produced, prepared, and applied, and that early evidence still needs larger controlled studies (Exosome review, PMC). In the United States, exosome products intended to treat diseases or conditions require FDA approval, and the FDA states that there are currently no FDA-approved exosome products (FDA consumer alert). The FDA's statement applies to the whole U.S. category rather than naming any single product. If you want to know more about the specific product used here, ask Dr. Lee directly at consultation.

Who Performs P198 Exosome Skin Booster at Doctorpetit Clinic Hongdae

Dr. Chae-ho Lee
Medical Director at Doctorpetit Clinic Hongdae

Exosome treatments at Doctorpetit Clinic Hongdae are performed by Dr. Chae-ho Lee, the Medical Director and the only physician at the clinic. His professional memberships include the Korean Society of Clinical Aesthetic Medicine, and skin boosters and biostimulators form one of his listed core areas of practice. He evaluates your skin condition, history, and goals before deciding whether the exosome booster is appropriate. The same doctor then performs the treatment and plans any later sessions.

Who Is a Good Candidate for the P198 Exosome Skin Booster?

The clinician decides suitability after looking at your skin, medical history, and goals. The treatment may suit:

• Adults who want to improve skin texture, hydration, elasticity, or overall skin quality.
• People showing early signs of skin aging who prefer a gradual, low-downtime approach.
• People with problem-prone skin, such as acne-prone or sensitive skin, who want a supportive treatment.
• Patients already planning laser or other skin-rejuvenation treatments who want a booster in the same plan.
• People who can commit to a course of at least three sessions.

The treatment may not be suitable, or may need to be postponed, for:

• Anyone with an active skin infection in the treatment area.
• People with certain allergies relevant to the product.
• People with uncontrolled medical conditions.
• Anyone with other factors that the doctor judges could increase treatment risk.
• People expecting proven, predictable results, given that independent evidence is limited.

What to Expect: Procedure, Recovery, and Results Timeline

Before your session

Discuss your medical history, allergies, medications, skin conditions, and goals with the clinician. You may be advised to avoid alcohol, smoking, and irritating skincare products in the days before treatment, and to arrive with clean skin.

The session, step by step

1. Consultation. Dr. Lee assesses your skin condition and treatment goals.
2. Preparation. The skin is cleansed and prepared.
3. Numbing. A topical anesthetic may be applied for comfort, depending on technique and sensitivity.
4. Application or injection. The exosome product is applied to, or injected into, the targeted areas.
5. Skin care. The treatment is intended to support skin renewal and overall skin quality.
6. Aftercare. The area is gently cared for, and simple instructions are given.

The procedure takes about 15 to 30 minutes, depending on whether other procedures are performed at the same visit. Mild discomfort, stinging, or a pinching sensation may be felt during injections.

Recovery and results timeline

When	What to expect
Same day	Most people return to usual activities shortly after treatment.
Days 1–3	Mild redness, pinpoint bruising, or swelling is common and settles as the skin calms.
Weeks 2–4	Gradual improvement may become noticeable after each session.
Every 3–4 weeks	The next session in the course is scheduled.
After 3 or more sessions	The overall result of the course can be judged; timing varies with skin condition.

Aftercare

Keep the treated area clean. For a short period, avoid excessive touching, rubbing, heat, strenuous exercise, and irritating skincare. Use gentle products and sun protection, and follow the specific instructions the clinic gives you.

Planning a trip

Because this is an outpatient treatment with little downtime, a long stay is not usually needed. A short stay of around two to three days in Korea may be enough for a session, depending on your plan. Since the clinic recommends at least three sessions at three- to four-week intervals, a full course usually means either repeat visits or a longer stay. You can generally travel once you feel comfortable and have no significant reaction.

Combining the P198 Exosome Skin Booster with Other Treatments

The clinic notes that the exosome booster may be combined with other skin-rejuvenation treatments, depending on your skin and goals:

• Laser & Skin Rejuvenation — the clinic states the exosome booster may be combined with laser treatments or microneedling.
• Microneedling — listed by the clinic as a possible partner treatment.
• Rejuran Injection (Salmon DNA / PN) and Hyaluronic Acid & Collagen Skin Boosters — other boosters may be considered in the same plan.

Session length depends partly on what is done together, which is why the clinic quotes a range. Dr. Lee decides what to pair, and in what order, after examining your skin.

Safety, Precision, and Clinic Standards

• Doctorpetit Clinic Hongdae became a Ministry of Health and Welfare registered institution for foreign patients in January 2023.
• Dr. Chae-ho Lee assesses every patient and performs every exosome treatment.
• The clinic states that it follows a 1:1 consultation principle before recommending any plan.
• The clinic describes the exosome booster for skin rejuvenation, collagen support, and texture.

Possible side effects and risks

Temporary redness, swelling, tenderness, sensitivity, bruising, or irritation can follow treatment. Less commonly, infection, prolonged redness or swelling, inflammatory reactions, allergic reactions, or other injection-related complications can occur. Contact the doctor promptly if you notice anything unusual.

The FDA encourages anyone who has a bad side effect after a product marketed as regenerative medicine, including exosome products, to report it, and warns that misleading information about these products is common online (FDA consumer alert). Because standardization across exosome products is lacking, results and side effects reported for one product should not be assumed for another (Exosome review, PMC).

The Bottom Line

• The P198 Exosome Healer is a skin booster built from stem-cell-culture exosomes in microparticle form.
• The clinic describes it for collagen support, texture, and problem-prone skin.
• Dr. Chae-ho Lee performs the treatment, which takes about 15 to 30 minutes with little downtime.
• At least three sessions three to four weeks apart are recommended, with gradual change over two to four weeks per session.
• Independent evidence is limited, and the FDA has not approved any exosome product in the United States.

Frequently Asked Questions

What makes an exosome booster different from other skin boosters?
It is built around exosomes from stem-cell culture fluid rather than hyaluronic acid or polynucleotides. The clinic describes it as supporting collagen and calming problem-prone skin, whereas hyaluronic acid boosters focus mainly on hydration.

How many sessions will I need?
The clinic recommends at least three sessions spaced three to four weeks apart. Your plan may differ after Dr. Lee assesses your skin.

Is there downtime?
Very little. Most people resume daily activities right away. Mild redness, pinpoint bruising, or swelling for one to three days is common.

When will I notice a difference?
Changes tend to appear gradually over two to four weeks after each session. The timing and degree vary with your skin and treatment plan.

Is the exosome booster FDA-approved?
No exosome product is currently FDA-approved in the United States, and the FDA regulates this category. Ask Dr. Lee about the product used and talk openly about your expectations.

Does the treatment hurt?
Mild discomfort, stinging, or pinching can be felt during injections, and the level varies from person to person. A topical numbing cream may be used, depending on the technique and how sensitive your skin is.

Can it be done on the same day as a laser treatment?
The clinic notes it may be combined with laser treatments, microneedling, or other boosters. Whether that suits you, and in which order, is decided at consultation.

Book a Consultation at Doctorpetit Clinic Hongdae

To find out whether an exosome skin booster in Seoul fits your skin, start with a 1:1 consultation with Dr. Chae-ho Lee, who will examine your skin and talk through realistic expectations before suggesting a plan. Consultations can take place in English, with interpretation available. The clinic occupies the eighth floor of the Wookdo Building at 151 Yanghwa-ro, Mapo-gu, and you step out of Hongik University Station Exit 1 right beside it. Make an appointment request, and read patient reviews as you plan your visit.

Disclaimer

Treatment suitability, expected results, recovery time, risks, and potential side effects vary by individual. The information provided is for general informational purposes and does not replace an in-person medical consultation. Patients should discuss their medical history, treatment goals, and individual circumstances with a qualified medical professional before undergoing treatment.

Sources & Further Reading

• PMC — Exosomes for Aesthetic Dermatology: A Comprehensive Literature Review and Update
• FDA — Consumer Alert on Regenerative Medicine Products Including Stem Cells and Exosomes